Opioid Metabolism
نویسندگان
چکیده
منابع مشابه
Opioid metabolism.
Clinicians understand that individual patients differ in their response to specific opioid analgesics and that patients may require trials of several opioids before finding an agent that provides effective analgesia with acceptable tolerability. Reasons for this variability include factors that are not clearly understood, such as allelic variants that dictate the complement of opioid receptors ...
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C appreciate that there is interplay between the actions of the different subtypes of receptor and hence the value of drugs which target multiple receptor subtypes. Abstract The opioid system comprises four receptor subtypes: m (MOP), k (KOP), d (DOP), now called the ‘classical’ opioid receptors, and the ‘non classical’ nociceptin/orphanin FQ peptide (N/OFQ) receptor (NOP). Selective endogenous...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2009
ISSN: 0025-6196
DOI: 10.4065/84.7.613